Bald 'n Sassy

Life is for the living. Live simply. Expect less.

Archive for the month “August, 2011”

Slight change of plans for round 5

Number 5 must be my lucky number.  It is exactly 5 days ago that I had another round of chemo treatment.  However there is a slight change of plans. The morning of the treatment started like any chemo session – a blood test.  I was hoping to have my favourite nurse to draw my precious blood but wasn’t my day.  I am not sure if she was rushed for time.  It was rather painful when she poked me with the needle. I could feel the blood flowing into the tube.  My arm was sore and weak for several hours – this is the first time I have felt any discomfort post a blood test.

So what is the change of plan you might ask.  The cancer marker level in my blood test showed a northward trend – about 10% increase from 56 to 62. This is not what I wanted to see.  My oncologist did not hesitate to advise me that we need to change the chemo drugs.  The plan is to go back using the set of chemo drugs administered last year.  The combo drugs are Carboplatin and Taxotere.  Before we proceeded with the treatment, she gave me an option of changing Taxotere to another drug called Taxol. From what she explained to me, Taxol is within the same class of Taxotere and used to various cancers such as breast and ovarian.  Taxol can be administered either on a weekly basis or every 3 weeks. I just can imagine not having a rest in between each session.  Plus my veins would not be able to recover in time.  I could have opted to insert a catheter but I can’t bring myself to go under the knife once again even if it is for very short duration.  I would be silly enough not to take up the 3 week plan. Mind you it takes around 4 to 4.5 hours to fully administer.   At least I have a longer period to recuperate in between each session.

Now that treatment plan took a detour, the next question I had to ask the doctor is how many rounds would I need to complete.  The answer I received is “Until the cancer markers has stabilized”.

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I am happy to say that the side effects for the new drugs are much easier to manage than the Japanese Campto drug.  No nausea, a slight headache and body aches for a day or two.  Mind you I am still very cautious about my immunity in the first post chemo.  My white blood cells has crept up a little higher but I am not completely out of the woods.

I am looking forward to walking out of the house for some natural Vitamin D tomorrow.  The other happy news is that I can fit in more swimming days in between treatments.

What will the results show today?

It’s Friday and today is round 5 of my chemo treatment. My body is starting to ache from the 2 consecutive days of swimming.  I am proud to that I can swim 40 laps each time. This is my personal best thus far and my minimum number of laps each time I swim.

Ok, swimming aside.  I am little anxious what my blood test results will be later this morning. The results will decide what course of action I will take.  Should there be minimal decrease in the cancer markers, then I may have to revert to using the Carboplatin and Taxotere combination used in my first chemo treatment last year.  If my memory serves me right, my oncologist mentioned that she will change to Taxol instead of Taxotere.  The white blood cells count will be the other indicator closely monitored. Although I feel physically fine, I am susceptible to catching any cold or virus’ very easily plus my body would have a tougher time to fight should I fall ill.  It doesn’t help that my sister and her daughter have not been well over the past week.  I just keep a good distance away when possible.  My brother in law has a sore ankle to add to the woes. So I have been helping out with the cooking and housework. Not a fun household to be in right now.

I am crossing my fingers and toes for a better blood test results.  It is a short post today.  I’ll be leaving shortly to head to the doctor’s.

Round number 4 – checked

Is it me or is timing flying past much faster.  It is exactly one week ago that I successfully completed my 4th chemo treatment.  Phew!  Overall the treatment well but there is a possibility a change in plans.

So here is the story.  As you may have learnt from my earlier posts, there is a blood test that is carried out prior to start of each session to decide how I am responding to the treatment plus the results will raise any concerns in my blood.  For me the key indicators are the cancer markers and white blood cells that I am most worried about.  I like to see a downward trend for the cancer markers and for the white blood cells level increased to a higher level.  As soon as my oncologist sat down with me to review the results for round 4, I was taken aback to see cancer markers increased by 10% from 49.9 to 56.3.  She was just as surprised as I am.  There are two possibilities that could see the markers spike up.

  • Fighting a viral infection.
  • The cancer cells has learnt to adapt to resist drug and mutate to generate new cancer cells.

I have been physically fine and not fallen ill in between treatments. As for the second point, cancer cells are incredibly intelligent to regenerate new cells in a matter of days.  In round 3, I postponed the treatment by 5 days simply because my white blood cells were too low and anemic.  In that short space of time, it is an opportunistic time for the cancer cells to adapt and learn to be resistant. I haven’t researched into this myself nor can I prove it.   Moreover the chemo drugs has  “expiry” date in terms of effectiveness.  In my case, the drug, Campto last for about 17 days or so. Delaying any further could pose further risk and lower the effectiveness.

So what does the above mean for me.  My doctor explained the options available.  First option is to change the chemo drug to the Carboplatin/Taxotere combo used in my first volume of chemo last year.  This means back to one round every 3 weeks and I would need to completed at most 4 rounds.  My white blood cells levels with this drug didn’t drop below the normal range.  Second choice is to use a complete new drug that is prescribed on a weekly dosage.  I am not too keen on this option because my veins would not be able to cope with the weekly poking.  As it is now my veins are under so much stress each time I have chemo plus I only have less than 2 weeks to rest before it all happens again.  In the event I choose to have his intense program, she strongly recommended for me to insert a catheter near my collarbone for much smoother and painless administration.  Oh boy!  Decisions decisions.

If I had to compare the choices, I would opt for number 1. And from past treatments, my white blood cells did not take a huge beating from the drugs.  There is a fine balancing act right now of making sure the drugs are working and still be somewhat strong enough to fight off a cold.

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I am just wondering with the modern medicine today, how come pharmaceutical companies haven’t thought of a wonder pill for white blood cells.

TGIF.  Have a good weekend everyone!

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